Slight alterations in microRNA sequences hold more information than previously thought

MicroRNA isoforms show population-specific and gender-specific signatures -– a finding that could affect how researchers view and study microRNAs. The team's findings have several implications: For researchers they suggest that the assays currently in the market do not necessarily capture the variant that is prevalent in the cells with which a researcher works. For patients, the findings represent an opportunity for a potentially significant advantage: the knowledge that a given patient has a different molecular profile than another patient with the same disease is a very important piece of information.



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