Clues to superbug evolution: Microbiologists sequence entire genome of a Klebsiella pneumoniae strain

Imagine going to the hospital with one disease and coming home with something much worse, or not coming home at all. With the emergence and spread of antibiotic-resistance pathogens, healthcare-associated infections have become a serious threat. On any given day about one in 25 hospital patients has at least one such infection and as many as one in nine die as a result. Microbiologists, for the first time, recently sequenced the entire genome of a Klebsiella pneumoniae strain, encoding New Delhi Metallo-beta-lactamase (NDM-1).



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